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[18F]myo-3

Development stage: Preclinical
Modality: Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration: Intravenous

Overview

[18F]myo-3 is one of eight new [18F]fluoro-inositol-based radiotracers developed for Positron Emission Tomography (PET) imaging. It features a propyl linker bearing fluorine-18, which can be O-alkylated on a hydroxyl group or C-branched on the cyclohexyl backbone. The radiotracer was synthesized in acetylated or hydroxylated form to modulate lipophilicity. It has undergone preliminary in vivo preclinical evaluation as a PET imaging agent in a breast tumor-bearing mouse model, suggesting its potential for monitoring breast cancer.

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